Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer
Author:
Affiliation:
1. School of Medicine, Trinity Biomedical Sciences Institute; Trinity College Dublin; Dublin 2 Ireland
2. Adjuvant Research Group, School of Biochemistry and Immunology; Trinity Biomedical Sciences Institute, Trinity College Dublin; Dublin 2 Ireland
Funder
Science Foundation Ireland (SFI) and National Children's Research Centre
SFI
SFI Research Centre, Advanced Materials and BioEngineering Research (AMBER)
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201545780/fullpdf
Reference95 articles.
1. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines;Schmitz;Immunity,2005
2. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo;Carriere;Proc. Natl. Acad. Sci. USA,2007
3. Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket;Roussel;EMBO Rep.,2008
4. The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription;Ali;J. Immunol.,2011
5. Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors-insight into heterotrimeric IL-1 signaling complexes;Lingel;Structure,2009
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