Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ ARE , IL6 / STAT ‐3, and NF‐κB / AP ‐1 signaling pathways-Reference-Cited by-同舟云学术

Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ ARE , IL6 / STAT ‐3, and NF‐κB / AP ‐1 signaling pathways

Published:2021-12-23 Issue:1 Volume:36 Page:488-505
ISSN:0951-418X
Container-title:Phytotherapy Research
language:en
Short-container-title:Phytotherapy Research

Author:

Abd El‐Ghafar Omnia A. M.¹,Hassanein Emad H. M.²,Ali Fares E. M.²^ORCID,Omar Zainab M. M.³,Rashwan Eman K.⁴,Mohammedsaleh Zuhair M.⁵^ORCID,Sayed Ahmed M.⁶

Affiliation:

1. Department of Pharmacology and Toxicology, Faculty of Pharmacy Nahda University Beni‐Suef Egypt

2. Department of Pharmacology and Toxicology, Faculty of Pharmacy Al‐Azhar University Assiut Egypt

3. Department of Pharmacology, College of Medicine Al‐Azhar University Assiut Egypt

4. Department of Physiology, College of Medicine Jouf University Sakaka Saudi Arabia

5. Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences University of Tabuk Tabuk Saudi Arabia

6. Biochemistry Laboratory, Chemistry Department, Faculty of Science Assiut University Assiut Egypt

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7355

Reference72 articles.

1. Acetovanillone prevents cyclophosphamide‐induced acute lung injury by modulating PI3K /Akt/ mTOR and Nrf2 signaling in rats

2. Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice

3. Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways

4. Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats

5. Methotrexate induced mitochondrial injury and cytochrome c release in rat liver hepatocytes

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