Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways-Reference-Cited by-同舟云学术

Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways

Published:2020-08-29 Issue:5 Volume:42 Page:493-503
ISSN:0892-3973
Container-title:Immunopharmacology and Immunotoxicology
language:en
Short-container-title:Immunopharmacology and Immunotoxicology

Author:

Abdel-Wahab Basel A.¹²,Ali Fares E. M.³^ORCID,Alkahtani Saad A.⁴,Alshabi Ali M.⁴,Mahnashi Mater H.⁵,Hassanein Emad H. M.³^ORCID

Affiliation:

1. Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia

2. Department of Medical Pharmacology, College of Medicine, Assiut University, Assiut, Egypt

3. Department of Pharmacology & Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt

4. Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia

5. Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/08923973.2020.1811307

Reference81 articles.

1. The methotrexate story: A paradigm for development of cancer chemotherapeutic agents

2. Preventing and Managing Toxicities of High-Dose Methotrexate

3. Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

4. A review of methotrexate-associated hepatotoxicity

5. Crocin ameliorates methotrexate-induced liver injury via inhibition of oxidative stress and inflammation in rats

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