A Validated Normal Phase LC Method for Enantiomeric Separation of Rasagiline Mesylate and Its (S )-Enantiomer on Cellulose Derivative-Based Chiral Stationary Phase

Author:

Sunil Reddy P.12,Sudhakar Babu K.2,Kumar Navneet1

Affiliation:

1. Dr. Reddy's Laboratories Ltd.; IPDO, Bachupally Hyderabad 500072 A.P India

2. Department of Chemistry; S. K. University; Anantapur 515055 A.P. India

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference11 articles.

1. U.S. Food and Drug Administration Guidance: Development of new stereoisomeric drugs 1992 http://www.fda.gov/drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm122883.htm

2. http://www.rxlist.com/azilect-drug.htm

3. Pharmacology and neuroprotective properties of rasagiline;Finberg;J Neural Transm Suppl,1996

4. The role of rasagiline in the treatment of Parkinson's disease;Leegwater-Kim;Clin Interv Aging,2010

5. Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis;Binda;J Med Chem,2005

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