The use of18O-exchange and base-catalyzedN-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Analytical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.4595/fullpdf
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4. Enzymatic peptidyl .alpha.-amidation proceeds through formation of an .alpha.-hydroxyglycine intermediate
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1. Metalloporphyrin-catalyzed hydroxylation of the N,N-dimethylamide function of the drug molecule SSR180575 to a stable N-methyl-N-carbinolamide;Comptes Rendus Chimie;2013-11
2. Dirlotapide as a model substrate to refine structure-based drug design strategies on CYP3A4-catalyzed metabolism;Bioorganic & Medicinal Chemistry Letters;2012-01
3. Current literature in mass spectrometry;Journal of Mass Spectrometry;2010-10
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