A chimeric HS4 insulator-scaffold attachment region enhances transgene expression in transfected Chinese hamster ovary cells-Reference-Cited by-同舟云学术

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A chimeric HS4 insulator-scaffold attachment region enhances transgene expression in transfected Chinese hamster ovary cells

Published:2017-11-06 Issue:12 Volume:7 Page:2021-2030
ISSN:2211-5463
Container-title:FEBS Open Bio
language:en
Short-container-title:FEBS Open Bio

Author:

Chen Si-jia¹,Wang Wen²³,Zhang Feng-yi⁴,Jia Yan-long²³,Wang Xiao-yin¹,Guo Xiao²,Chen Shao-Nan¹,Gao Jian-hui¹,Wang Tian-Yun¹³

Affiliation:

1. Department of Biochemistry and Molecular Biology; Xinxiang Medical University; Henan China

2. Pharmacy Collage; Xinxiang Medical University; Henan China

3. Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine; Xinxiang Medical University; China

4. Grade 2012; The Third Clinical Medical College of Xinxiang Medical University; Henan China

Funder

National Natural Science Foundation of China

Plan for Scientific Innovation Talent of Henan Province, China

Plan of Scientific and Technological Innovation Team for University, Henan Province, China

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology

Reference44 articles.

1. Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow;Golabgir;Biotechol Adv,2016

2. Molecular characterization of a human matrix attachment region that improves transgene expression in CHO cells;Sun;Gene,2016

3. Improved recombinant antibody production by CHO cells using a production enhancer DNA element with repeated transgene integration at a predetermined chromosomal site;Kawabe;J Biosci Bioeng,2016

4. Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease;Stein;Nat Med,2010

5. Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells;Santilli;Mol Ther,2011

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1. Combination of MAR and intron increase transgene expression of episomal vectors in CHO cells;Biotechnology Journal;2023-08-21

2. Development of an Expression Vector Engineering Strategy Based on tDNA Insulator Element for the Stable Expression of Vascular Endothelial Growth Factor Receptor-Fc Fusion Protein;Monoclonal Antibodies in Immunodiagnosis and Immunotherapy;2023-08-01

3. Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells;Frontiers in Bioengineering and Biotechnology;2022-05-26

4. Enhanced Transgene Expression by Optimization of Poly A in Transfected CHO Cells;Frontiers in Bioengineering and Biotechnology;2022-01-24

5. Fusion with matrix attachment regions enhances expression of recombinant protein in human HT-1080 cells;Journal of Bioscience and Bioengineering;2020-11

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