Quantitative determination of duloxetine and its metabolite in rat plasma by HPLC-MS/MS

Author:

Chae Jung-woo1,Baek Hyun-moon1,Kim Sang Kyum1,Kang Ho-il2,Kwon Kwang-il1

Affiliation:

1. College of Pharmacy; Chungnam National University; Daejeon; Korea

2. Division of Pharmacological Research; National Institute of Food and Drug Safety Evaluation; Osong; Korea

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference7 articles.

1. Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma;Chae;Journal of Chromatography B,2012

2. Quantitative determination of aceclofenac and its three major metabolites in rat plasma by HPLC-MS/MS;Kim;Journal of Separation Science,2012

3. Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects;Lantz;Drug Metabolism and Disposition,2003

4. Determination of duloxetine in human plasma via LC/MS and subsequent application to a pharmacokinetic study in healthy Chinese volunteers;Ma;Clinica Chimica Acta,2007

5. Determination of duloxetine in rat plasma for pharmacokinetic study by developing a highly sensitive method using liquid chromatography-electrospray ionization tandem mass spectrometry;Radhe;International Journal of Research in Pharmaceutical Sciences,2012

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