Improving expression of recombinant human IGF-1 using IGF-1R knockout CHO cell lines

Author:

Romand Sandrine1,Jostock Thomas1,Fornaro Mara2,Schmidt Joerg3,Ritter Anett1,Wilms Burkhard1,Laux Holger1

Affiliation:

1. Integrated Biologics Profiling; Novartis Pharma; Klybeckstrasse 141 Basel 4057 Switzerland

2. Musculoskeletal Diseases; Novartis Institute for BioMedical Research; Basel Switzerland

3. Cell and Gene Therapies; Novartis Pharma; Basel Switzerland

Funder

Novartis

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Recombinant therapeutic proteins degradation and overcoming strategies in CHO cells;Applied Microbiology and Biotechnology;2024-01-29

2. Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris;Applied Microbiology and Biotechnology;2023-06-01

3. CRISPR‐interceded CHO cell line development approaches;Biotechnology and Bioengineering;2023-01-12

4. Life at the periphery: what makes CHO cells survival talents;Applied Microbiology and Biotechnology;2022-08-30

5. Reengineering of the CRISPR/Cas System;The CRISPR/Cas Tool Kit for Genome Editing;2022

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