Metformin Represses Interferonopathy Through Suppression of Melanoma Differentiation-Associated Protein 5 and Mitochondrial Antiviral Signaling Protein Activation: Comment on the Article by Wang et al

Author:

Su Yu-Jih1,Lin Hung-Yu1,Weng Shao-Wen1,Lu Cheng-Hsien1,Lin Ching-Yi1,Chiu Wen-Chan1,Wang Pei-Wen1

Affiliation:

1. Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine; Kaohsiung Taiwan China

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference6 articles.

1. Neutrophil extracellular trap mitochondrial DNA and its autoantibody in systemic lupus erythematosus and a proof-of-concept trial of metformin;Wang;Arthritis Rheumatol,2015

2. Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus;Su;J Transl Med,2014

3. IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling;Lazear;PLoS Pathog,2013

4. Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies;Hasan;Pharmacol Res,2016

5. The creation of cybrids harboring mitochondrial haplogroups in the Taiwanese population of ethnic Chinese background: an extensive in vitro tool for the study of mitochondrial genomic variations;Lin;Oxid Med Cell Longev

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