Solid-phase organic synthesis of chiral, non-racemic 1,2,4-trisubstituted 1,4-diazepanes with high σ1 receptor affinity
Author:
Affiliation:
1. Institut für Pharmazeutische und Medizinische Chemie; Universität Münster; Münster Germany
2. Cells-in-Motion Cluster of Excellence (EXC 1003-CiM); Westfälische Wilhelms-Universität Münster; Münster Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Drug Discovery,Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201700334/fullpdf
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1. Naltrexone fails to antagonize the σ effects of PCP and SKF 10,047 in the dog
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4. Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders
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