Synthesis and Biological Evaluation of Some New 2,5-Substituted 1-Ethyl-1H-benzoimidazole Fluorinated Derivatives as Direct Thrombin Inhibitors-Reference-Cited by-同舟云学术

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Synthesis and Biological Evaluation of Some New 2,5-Substituted 1-Ethyl-1H-benzoimidazole Fluorinated Derivatives as Direct Thrombin Inhibitors

Published:2015-03-30 Issue:5 Volume:348 Page:353-365
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Li Meilin¹,Ren Yujie¹

Affiliation:

1. College of Chemical and Environmental Engineering; Shanghai Institute of Technology; Shanghai China

Funder

Science and Technology Commission of Shanghai Municipality

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201400463/fullpdf

Reference35 articles.

1. Fibrinogen and fibrin structure and functions

2. The central role of thrombin in hemostasis

3. Mechanisms of platelet activation by thrombin: A short history

4. Dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: NICE guidance

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1. Current perspectives and trend of computer-aided drug design: a review and bibliometric analysis;International Journal of Surgery;2024-03-19

2. MXene-sensitized electrochemiluminescence sensor for thrombin activity detection and inhibitor screening;Microchimica Acta;2023-07-27

3. Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs;European Journal of Medicinal Chemistry;2022-01

4. The Research Progress of Direct Thrombin Inhibitors;Mini-Reviews in Medicinal Chemistry;2020-11-10

5. Identify thrombin inhibitor with novel skeleton based on virtual screening study;Journal of Biomolecular Structure and Dynamics;2020-09-02

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