New CYP17 Hydroxylase Inhibitors: Synthesis, Biological Evaluation, QSAR, and Molecular Docking Study of New Pregnenolone Analogs-Reference-Cited by-同舟云学术

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New CYP17 Hydroxylase Inhibitors: Synthesis, Biological Evaluation, QSAR, and Molecular Docking Study of New Pregnenolone Analogs

Published:2014-09-24 Issue:12 Volume:347 Page:896-907
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Al-Masoudi Najim A.¹,Ali Dawood S.¹,Saeed Bahjat²,Hartmann Rolf W.³,Engel Matthias³,Rashid Sajid⁴,Saeed Aamer⁵

Affiliation:

1. Department of Chemistry; College of Science; University of Basrah; Basrah Iraq

2. Department of Chemistry; College of Education; University of Basrah; Basrah Iraq

3. Institut für Pharmazeutische und Medizinische Chemie; Universität des Saarlandes; Saarbrücken Germany

4. National Center for Bioinformatics; Quaid-i-Azam University; Islamabad Pakistan

5. Department of Chemistry; Quaid-i-Azam University; Islamabad Pakistan

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201400255/fullpdf

Reference45 articles.

1. Inhibitors of Steroidal Cytochrome P450 Enzymes as Targets for Drug Development

2. CYP17 Inhibitors for Prostate Cancer Treatment – An Update

3. Synthesis of novel C17 steroidal carbamates

4. Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors

5. 17α-Hydroxylase/17,20-Lyase (P450 ) Inhibitors in the Treatment of Prostate Cancer: A Review

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4. Synthesis, DFT study, molecular docking and drug-likeness analysis of the heteroaryl substituted new pregnenolone derivatives;Journal of Molecular Structure;2022-07

5. Synthesis, In Vitro Anti-HIV Activity, Cytotoxicity, and Computational Studies of Some New Steroids and Their Pyrazoline and Oxime Analogues;Russian Journal of Bioorganic Chemistry;2020-09

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