Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR-γ modulators-Reference-Cited by-同舟云学术

Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR-γ modulators

Published:2018-02-05 Issue:3-4 Volume:351 Page:1700223
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Naim Mohd. Javed¹,Alam Ozair¹^ORCID,Alam Md. Jahangir¹,Shaquiquzzaman Mohammad¹,Alam Md. Mumtaz¹^ORCID,Naidu Vegi Ganga Modi²

Affiliation:

1. Medicinal Chemistry and Molecular Modelling Lab, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research; Jamia Hamdard; New Delhi India

2. Department of Pharmacology and Toxicology; National Institute of Pharmaceutical Education and Research; Hyderabad India

Funder

DST-SERB, New Delhi

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Reference44 articles.

1. Antidiabetic effect of novel benzenesulfonylureas as PPAR-γ agonists and their anticancer effect

2. Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: Synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression

3. Novel “Second-Generation” Approaches for the Control of Type 2 Diabetes

4. Discovery of a Potent, Highly Selective, and Orally Efficacious Small-Molecule Activator of the Insulin Receptor

5. Synthesis and biological activity of [[(heterocycloamino)alkoxy] benzyl]-2,4-thiazolidinediones as PPARγ agonists

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