Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: Synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression-Reference-Cited by-同舟云学术

Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: Synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression

Published:2014-07 Issue:14 Volume:24 Page:3034-3042
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Nazreen Syed,Alam Mohammad Sarwar,Hamid Hinna,Yar Mohammad Shahar,Dhulap Abhijeet,Alam Perwez,Pasha M.A.Q.,Bano Sameena,Alam Mohammad Mahboob,Haider Saqlain,Kharbanda Chetna,Ali Yakub,Pillai K.K.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Novel “Second-Generation” Approaches for the Control of Type 2 Diabetes

2. Discovery of a Potent, Highly Selective, and Orally Efficacious Small-Molecule Activator of the Insulin Receptor

3. Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents

4. [[.omega.-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents

5. Synthesis and biological activity of novel thiazolidinediones

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