Predosing with the unlabeled “inactive” enantiomer as a tool for improvement of the PET signal

Author:

Elfving Betina,Bjørnholm Berith,Knudsen Gitte M.

Funder

1991 Pharmacy Foundation

Health Insurance Fund

Lundbeck Foundation

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference7 articles.

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2. Binding characteristics of selective serotonin reuptake inhibitors with relation to emission tomography studies;Elfving;Synapse,2001

3. Evaluation of S-[11C]citalopram as a radioligand for in vivo labelling of 5-hydroxytryptamine uptake sites;Hume;Nucl Med Biol,1992

4. Effect of a specific 5-HT uptake inhibitor, citalopram (lu 10-171), on [3H]-5-HT uptake in rat brain synaptosomes in vitro;Hyttel;Psychopharmacology,1978

5. The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer;Hyttel;J Neural Transm Gen Sect,1992

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