A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo-Reference-Cited by-同舟云学术

A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo

Published:2019-12-13 Issue:7 Volume:15 Page:585-592
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Gobbi Luca¹^ORCID,Mercier Joël²,Bang‐Andersen Benny³,Nicolas Jean‐Marie²,Reilly John⁴,Wagner Björn¹,Whitehead David⁴^ORCID,Briard Emmanuelle⁴^ORCID,Maguire R. Paul²^ORCID,Borroni Edilio¹,Auberson Yves P.⁴^ORCID

Affiliation:

1. Pharma Research and Early DevelopmentRoche Innovation Center Basel F. Hoffmann-La Roche Ltd. 4070 Basel Switzerland

2. UCB Early SolutionsUCB Biopharma sprl 1420 Braine-l'Alleud Belgium

3. Molecular Discovery and InnovationH. Lundbeck A/S 9 Ottiliavej 2500 Valby Denmark

4. Global Discovery ChemistryNovartis Institutes for BioMedical Research Fabrikstrasse 2 4056 Basel Switzerland

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900608

Reference61 articles.

2. The Use of 18F-FDG PET in the Diagnosis of Cardiac Sarcoidosis: A Systematic Review and Metaanalysis Including the Ontario Experience

3. 18F-FDG PET/CT Imaging In Oncology

4. Effectiveness and Safety of 18F-FDG PET in the Evaluation of Dementia: A Review of the Recent Literature

5. Imaging the GABA-Benzodiazepine Receptor Subtype Containing the α5-Subunit In Vivo with [11C]Ro15 4513 Positron Emission Tomography

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system;Journal of Labelled Compounds and Radiopharmaceuticals;2022-09-29

2. Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs;Molecules;2022-05-16

3. The Application of in silico Methods for Prediction of Blood-Brain Barrier Permeability of Small Molecule PET Tracers;Frontiers in Nuclear Medicine;2022-03-25

4. Design, Synthesis, and Biological Evaluation of 4,4’-Difluorobenzhydrol Carbamates as Selective M1 Antagonists;Pharmaceuticals;2022-02-18

5. Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging;Journal of Medicinal Chemistry;2022-01-28