Genetic characterization of T-PLL reveals two major biologic subgroups andJAK3mutations as prognostic marker

Author:

Stengel Anna1,Kern Wolfgang1,Zenger Melanie1,Perglerová Karolína2,Schnittger Susanne1,Haferlach Torsten1,Haferlach Claudia1

Affiliation:

1. MLL Munich Leukemia Laboratory; Max-Lebsche-Platz 31 Munich 81377 Germany

2. MLL2 S.R.O., KCD4; Kolbenova 609/40, 190 00 Praha 9 Czech Republic

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference56 articles.

1. TP53 is frequently altered by methylation, mutation, and/or deletion in acute lymphoblastic leukaemia;Agirre;Mol Carcinog,2003

2. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL);Bene;Leukemia,1995

3. Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia;Bergmann;Genes Chromosomes Cancer,2014

4. Molecular and cellular mechanisms of T cell development;Bommhardt;Cell Mol Life Sci,2004

5. Ataxia telangiectasia gene mutations in leukaemia and lymphoma;Boultwood;J Clin Pathol,2001

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