Assessment of the Pig-a , micronucleus, and comet assay endpoints in rats treated by acute or repeated dosing protocols with procarbazine hydrochloride and ethyl carbamate-Reference-Cited by-同舟云学术

Assessment of the Pig-a , micronucleus, and comet assay endpoints in rats treated by acute or repeated dosing protocols with procarbazine hydrochloride and ethyl carbamate

Published:2018-09-21 Issue:1 Volume:60 Page:56-71
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ. Mol. Mutagen.

Author:

Chen Gaofeng¹²,Wen Hairuo¹,Mao Zhihui¹²,Song Jie¹,Jiang Hua¹,Wang Weifan¹,Yang Ying¹,Miao Yufa¹,Wang Chao¹,Huang Zhiying²,Wang Xue¹

Affiliation:

1. Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control; Beijing People's Republic of China

2. Center of Safety Evaluation on New Drug, School of Pharmaceutical Science, Sun Yat-sen University; Guangzhou People's Republic of China

Funder

Ministry of Science and Technology (MOST) of the People's Republic of China

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/em.22227/fullpdf

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4. Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate;Bemis;Mutagenesis,2015

5. Modulation of urethane (ethyl carbamate) carcinogenicity by ethyl alcohol: A review;Benson;Int J Toxicol,1997

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