Integrated In Vivo Genotoxicity Assessment of Procarbazine Hydrochloride Demonstrates Induction of Pig‐a and LacZ Mutations, and Micronuclei, in MutaMouse Hematopoietic Cells-Reference-Cited by-同舟云学术

Integrated In Vivo Genotoxicity Assessment of Procarbazine Hydrochloride Demonstrates Induction of Pig‐a and LacZ Mutations, and Micronuclei, in MutaMouse Hematopoietic Cells

Published:2019-01-18 Issue: Volume: Page:
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ Mol Mutagen

Author:

Maurice Clotilde¹,Dertinger Stephen D.²,Yauk Carole L.¹,Marchetti Francesco¹^ORCID

Affiliation:

1. Environmental Health Science and Research BureauHealth Canada Ottawa Ontario Canada

2. Litron Laboratories Rochester New York

Funder

Natural Sciences and Engineering Research Council of Canada

Health Canada

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22271

Reference34 articles.

1. Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors

2. Characterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing

3. Genetic toxicity of procarbazine in bacteria and yeast

4. Assessment of the Pig-a , micronucleus, and comet assay endpoints in rats treated by acute or repeated dosing protocols with procarbazine hydrochloride and ethyl carbamate

5. Procarbazine is a potent mutagen at the heterozygous thymidine kinase (tk+/−) locus of mouse lymphoma assay

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1. Procarbazine-induced Genomic Toxicity in Hodgkin Lymphoma Survivors;2024-06-05

2. Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride;Archives of Toxicology;2023-06-21

3. Duplex Sequencing Provides Detailed Characterization of Mutation Frequencies and Spectra in the Bone Marrow of MutaMouse Males Exposed to Procarbazine Hydrochloride;2023-02-23

4. Recent advances in γH2AX biomarker-based genotoxicity assays: A marker of DNA damage and repair;DNA Repair;2021-12

5. The 28 + 28 day design is an effective sampling time for analyzing mutant frequencies in rapidly proliferating tissues of MutaMouse animals;Archives of Toxicology;2021-01-28