A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia-Reference-Cited by-同舟云学术

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A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

Published:2016-10-13 Issue:11 Volume:5 Page:3031-3040
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Med

Author:

Reed Gregory A.¹,Schiller Gary J.²,Kambhampati Suman¹,Tallman Martin S.³,Douer Dan³,Minden Mark D.⁴,Yee Karen W.⁴,Gupta Vikas⁴,Brandwein Joseph⁴⁵,Jitkova Yulia⁴,Gronda Marcela⁴,Hurren Rose⁴,Shamas‐Din Aisha⁴,Schuh Andre C.⁴,Schimmer Aaron D.⁴

Affiliation:

1. University of Kansas Cancer Center Kansas City Kansas

2. David Geffen School of Medicine at UCLA Los Angeles California

3. Leukemia ServiceDepartment of MedicineOncology and Pathogenesis ProgramMemorial Sloan Kettering Cancer Center New York New York

4. Princess Margaret Cancer CentreUniversity Health Network Toronto Ontario Canada

5. Department of MedicineUniversity of Alberta Edmonton Alberta Canada

Funder

National Institutes of Health

Leukemia and Lymphoma Society

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.845

Reference30 articles.

1. Acute Myeloid Leukemia

2. Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

3. BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

4. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

5. AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

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