TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target

Author:

Chen Lin‐Yu1ORCID,Huang Rui‐Lan2ORCID,Chan Michael WY34,Yan Pearlly S5,Huang Tien‐Shuo2,Wu Ren‐Chin6,Suryo Rahmanto Yohan7ORCID,Su Po‐Hsuan2ORCID,Weng Yu‐Chun2,Chou Jian‐Liang3,Chao Tai‐Kuang8,Wang Yu‐Chi9,Shih Ie‐Ming710ORCID,Lai Hung‐Cheng1211

Affiliation:

1. Graduate Institute of Life SciencesNational Defense Medical Center Taipei Taiwan

2. Department of Obstetrics and GynecologyShuang Ho Hospital, Taipei Medical University New Taipei City Taiwan

3. Department of Biomedical SciencesNational Chung Cheng University Chiayi Taiwan

4. Institute of Molecular BiologyNational Chung Cheng University Chiayi Taiwan

5. Department of Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer CenterThe Ohio State University Columbus OH USA

6. Department of PathologyChang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan

7. Department of PathologySidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions Baltimore MD USA

8. Department of PathologyTri‐Service General Hospital, National Defense Medical Center Taipei Taiwan

9. Obstetrics and GynecologyTri‐Service General Hospital, National Defense Medical Center Taipei Taiwan

10. Department of Gynecology and ObstetricsJohns Hopkins Medical Institutions Baltimore MD USA

11. Department of Obstetrics and Gynecology, School of Medicine, College of MedicineTaipei Medical University Taipei Taiwan

Funder

National Health Research Institutes

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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