Prognostic value of the proliferation marker Ki-67 in laryngeal carcinoma: Results of the Accelerated Radiotherapy with Carbogen Breathing and Nicotinamide phase III randomized trial

Author:

Rademakers Saskia E.1,Hoogsteen Ilse J.1,Rijken Paul F.1,Terhaard Chris H.2,Doornaert Patricia A.3,Langendijk Johannes A.4,van den Ende Piet5,van der Kogel Albert J.1,Bussink Johan1,Kaanders Johannes H.1

Affiliation:

1. Department of Radiation Oncology; Radboud University Nijmegen Medical Centre; Nijmegen The Netherlands

2. Department of Radiation Oncology; University Medical Center Utrecht; Utrecht The Netherlands

3. Department of Radiation Oncology; VU University Medical Center; Amsterdam The Netherlands

4. Department of Radiation Oncology; University Medical Center Groningen; Groningen The Netherlands

5. Department of Radiation Oncology; Maastricht University Medical Center; Maastricht The Netherlands

Funder

Dutch Cancer Society

Publisher

Wiley

Subject

Otorhinolaryngology

Reference20 articles.

1. Prognostic relevance of cell proliferation in head and neck tumors;Pich;Ann Oncol,2004

2. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer;Kaanders;Cancer Res,2002

3. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study;Nordsmark;Radiother Oncol,2005

4. Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma;Hoogsteen;Clin Cancer Res,2005

5. Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial;Janssens;J Clin Oncol,2012

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