A quinazoline‐based bromodomain inhibitor, CN210 , ameliorates indomethacin‐induced ileitis in mice by inhibiting inflammatory cytokine expression-Reference-Cited by-同舟云学术

A quinazoline‐based bromodomain inhibitor, CN210 , ameliorates indomethacin‐induced ileitis in mice by inhibiting inflammatory cytokine expression

Published:2021-06 Issue:8 Volume:82 Page:1235-1246
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev Res

Author:

Noguchi Takehisa¹,Hidaka Kyosuke¹,Kobayashi Satsuki¹,Matsumoto Kenjiro¹,Yoshioka Makoto²,Hu Xin³,Maloney David J.³,Yang Shyh‐Ming³,Kato Shinichi¹^ORCID

Affiliation:

1. Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics Kyoto Pharmaceutical University Kyoto Japan

2. ConverGene LLC Cambridge Maryland USA

3. National Center for Advancing Translational Sciences, National Institutes of Health Rockville Maryland USA

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21838

Reference51 articles.

2. Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors

3. BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses

4. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans

5. NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

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