Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice-Reference-Cited by-同舟云学术

Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice

Published:2020-05-12 Issue:9 Volume:35 Page:1812-1823
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Chen Chung‐Hwan¹²³⁴⁵^ORCID,Lai Chao‐Han⁶^ORCID,Hong Yi‐Kai⁷,Lu Jui‐Ming⁸,Lin Sung‐Yen¹²³⁴⁵,Lee Tien‐Ching¹^ORCID,Chang Lan‐Yun⁸,Ho Mei‐Ling¹⁵⁹,Conway Edward M¹⁰,Wu Hua‐Lin⁸,Cheng Tsung‐Lin¹⁵⁹^ORCID

Affiliation:

1. Orthopaedic Research Center Kaohsiung Medical University Kaohsiung Taiwan

2. Department of Orthopedics, College of Medicine Kaohsiung Medical University Kaohsiung Taiwan

3. Division of Adult Reconstruction Surgery, Department of Orthopedics Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung Taiwan

4. Department of Orthopedics, Kaohsiung Municipal Ta‐Tung Hospital Kaohsiung Medical University Kaohsiung Taiwan

5. Regenerative Medicine and Cell Therapy Research Center Kaohsiung Medical University Kaohsiung Taiwan

6. Department of Surgery National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan

7. Institute of Basic Medical Sciences, College of Medicine National Cheng Kung University Tainan Taiwan

8. Department of Biochemistry and Molecular Biology, College of Medicine National Cheng Kung University Tainan Taiwan

9. Department of Physiology, School of Medicine, College of Medicine Kaohsiung Medical University Kaohsiung Taiwan

10. Centre for Blood Research, Faculty of Medicine, Life Sciences Institute University of British Columbia Vancouver BC Canada

Funder

Kaohsiung Medical University

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.4036

Reference42 articles.

1. Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages

2. Thrombomodulin is synthesized by osteoblasts, stimulated by 1,25-(OH)2D3 and activates protein C at their cell membrane.

3. Thrombomodulin expression by human keratinocytes. Induction of cofactor activity during epidermal differentiation.

4. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

5. Thrombomodulin

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