Optimizing Central Nervous System Drug Development Using Molecular Imaging

Author:

Hargreaves RJ1,Hoppin J2,Sevigny J1,Patel S1,Chiao P1,Klimas M3,Verma A1

Affiliation:

1. Biogen; Cambridge Massachusetts USA

2. inviCRO, LLC; Boston Massachusetts USA

3. Merck Research Laboratories; West Point Pennsylvania USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference75 articles.

1. De Masi , J.A. Grabowski , H.G. Hansen , R.W. Innovation in the pharmaceutical industry: new estimates of R&D costs http://csdd.tufts.edu/files/uploads/Tufts_CSDD_briefing_on_RD_cost_study_-_Nov_18,_2014.pdf http://csdd.tufts.edu/files/uploads/cost_study_backgrounder.pdf 2014

2. Booth , B. A billion here, a billion there. The cost of making a drug revisited http://www.forbes.com/sites/brucebooth/2014/11/21/a-billion-here-a-billion-there-the-cost-of-making-a-drug-revisited/ 2014

3. Kielstra , P. The innovation imperative in biopharma. Reinventing biopharma strategies for an evolving marketplace http://www.economistinsights.com/sites/default/files/legacy/mgthink/downloads/The%20Innovation%20imperative%20in%20biopharma.pdf

4. Clinical biomarkers in drug discovery and development;Frank;Nat. Rev. Drug Discov.,2003

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