Evaluation of species difference in peripheral lymphocyte reduction effect of CS-0777, a sphingosine 1-phosphate receptor modulator, based on a pharmacokinetic/pharmacodynamic model analysis-Reference-Cited by-同舟云学术

Evaluation of species difference in peripheral lymphocyte reduction effect of CS-0777, a sphingosine 1-phosphate receptor modulator, based on a pharmacokinetic/pharmacodynamic model analysis

Published:2016-11-14 Issue:9 Volume:37 Page:561-573
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Inaba Shin-ichi¹,Goto Maki¹,Tanaka-takanaka Kaoru¹,Tanaka Hisako²,Tomisato Wataru³,Yuita Hiroshi⁴,Doi-Komuro Hiromi³,Inoue Ryotaku³,Oshima Keiko⁴,Kagari Takashi³,Shimozato Takaichi³,Izumi Takashi¹

Affiliation:

1. Drug Metabolism & Pharmacokinetics Research Laboratories; Daiichi Sankyo Co., Ltd; Tokyo Japan

2. Center for Pharmaceutical and Biomedical Analysis, Daiichi Sankyo RD Novare Co., Ltd; Tokyo Japan

3. Frontier Research Laboratories; Daiichi Sankyo Co., Ltd; Tokyo Japan

4. Oncology Research Laboratories; Daiichi Sankyo Co., Ltd; Tokyo Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.2048/fullpdf

Reference19 articles.

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2. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs;Cyster;Annu Rev Immunol,2005

3. The immune modulator FTY720 targets sphingosine 1-phosphate receptors;Brinkmann;J Biol Chem,2002

4. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1;Matloubian;Nature,2004

5. Purification and identification of activating enzymes of CS-0777, a selective sphingosine 1-phosphate receptor 1 modulator, in erythrocytes;Yonesu;J Biol Chem,2011