Sphingosine-1-phosphate: an enigmatic signalling lipid
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm1103.pdf
Reference91 articles.
1. Thudichum, J. L. W. A Treatise on the Chemical Constitution of Brain. 149 (Bailliere, Tindall and Cox, London, 1884).
2. Stoffel, W. & Assmann, G. Metabolism of sphingoid bases, XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine-1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate. Hoppe-Seyler's Z. Physiol. Chem. 351, 1041–1049 (1970).
3. Zhang, H. et al. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 114, 155–167 (1991).
4. Olivera, A. & Spiegel, S. Sphingosine-1-phosphate as a second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365, 557–560 (1993). This was a pioneering study that showed that S1P was a signalling molecule.
5. Cuvillier, O. et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381, 800–803 (1996). This was the first evidence that S1P can suppress apoptosis and proposed the concept of the sphingolipid rheostat.
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