Mutagenicity of the human carcinogen treosulphan, and its hydrolysis product, dl-1,2:3,4-diepoxybutane in mammalian cells
Author:
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology
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4. Activity of L-threitol-1,4-bismethanesulfonate on barley chromosomes in relation to chemical transformation during treatment
5. Chromosome Breakage with Two Isomers of l-Threitol 1,4-bismethanesulphonate in Plants
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1. A simplified method for detection of N ‐terminal valine adducts in patients receiving treosulfan;Rapid Communications in Mass Spectrometry;2019-10-28
2. Kinetics of in Vitro Guanine-N7-Alkylation in Calf Thymus DNA by (2S,3S)-1,2-Epoxybutane-3,4-diol 4-methanesulfonate and (2S,3S)-1,2:3,4-Diepoxybutane: Revision of the Mechanism of DNA Cross-Linking by the Prodrug Treosulfan;Molecular Pharmaceutics;2019-04-23
3. N-7-Guanine Adduct of the Active Monoepoxide of Prodrug Treosulfan: First Synthesis, Characterization, and Decomposition Profile Under Physiological Conditions;Journal of Pharmaceutical Sciences;2018-11
4. Ocular disposition of treosulfan and its active epoxy-transformers following intravenous administration in rabbits;Drug Metabolism and Pharmacokinetics;2016-10
5. A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins;Mutation Research/Genetic Toxicology and Environmental Mutagenesis;2011-03
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