N-7-Guanine Adduct of the Active Monoepoxide of Prodrug Treosulfan: First Synthesis, Characterization, and Decomposition Profile Under Physiological Conditions-Reference-Cited by-同舟云学术

N-7-Guanine Adduct of the Active Monoepoxide of Prodrug Treosulfan: First Synthesis, Characterization, and Decomposition Profile Under Physiological Conditions

Published:2018-11 Issue:11 Volume:107 Page:2927-2937
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Romański Michał,Girreser Ulrich,Teżyk Artur,Główka Franciszek K.

Funder

Poznan University of Medical Sciences

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference29 articles.

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2. Treosulfan and fludarabine conditioning for hematopoietic stem cell transplantation in children with primary immunodeficiency: UK experience;Slatter;Biol Blood Marrow Transplant,2018

3. High-dose treosulfan in conditioning prior to hematopoietic stem cell transplantation;Główka;Expert Opin Investig Drugs,2010

4. Activation of prodrug treosulfan at pH 7.4 and 37°C accompanied by hydrolysis of its active epoxides: kinetic studies with clinical relevance;Romański;J Pharm Sci,2015

5. Kinetic and mechanistic study of the pH-dependent activation (epoxidation) of prodrug treosulfan including the reaction inhibition in a borate buffer;Romański;J Pharm Sci,2017

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2. Nonenzymatic hydrolysis of 1,2:3,4‐diepoxybutane: A kinetic study including pH, temperature, and ion effects;International Journal of Chemical Kinetics;2023-08

3. Population pharmacokinetic approach for evaluation of treosulfan and its active monoepoxide disposition in plasma and brain on the basis of a rat model;Pharmacological Reports;2020-05-30

4. Treosulfan in combination with fludarabine as part of conditioning treatment prior to allogeneic hematopoietic stem cell transplantation;Drugs of Today;2020

5. Liquid chromatography–tandem mass spectrometry method for simultaneous determination of three N-7-guanine adducts of the active epoxides of prodrug treosulfan in DNA in vitro;Talanta;2019-06