Lithium adduct as precursor ion for sensitive and rapid quantification of 20 (S)-protopanaxadiol in rat plasma by liquid chromatography/quadrupole linear ion trap mass spectrometry and application to rat pharmacokinetic study

Author:

Bao Yuanwu1,Wang Quanying2,Tang Pingming2

Affiliation:

1. Sundia MediTech Company Ltd.; 388 Jialilue Road Building 9, Zhangjiang High-Tech Park; Shanghai; 201203; China

2. Suzhou Kangrun Pharmaceutical Testing Service, Inc.; Jiangsu; 215200; China

Publisher

Wiley

Subject

Spectroscopy

Reference29 articles.

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2. Ginseng compounds: an update on their molecular mechanisms and medical applications;Lü;Curr. Vasc. Pharmacol.,2009

3. Research progress on pharmacological activity of 20(S)-protopanaxadiol;Mao;Chin J. Exp. Trad. Med. Formulae,2011

4. Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside-Rg3, of red ginseng [J];Mochizuki;Biol. Pharm. Bull.,1995

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