Polishing approach with fully connected flow-through purification for therapeutic monoclonal antibody

Author:

Ichihara Takamitsu1,Ito Takao2,Gillespie Christopher3

Affiliation:

1. Astellas Pharma Inc.; Tokyo Japan

2. Process Solutions; Merck Ltd.; Tokyo Japan

3. Process Solutions; MilliporeSigma; Bedford MA USA

Publisher

Wiley

Subject

Bioengineering,Environmental Engineering,Biotechnology

Reference12 articles.

1. The state of the Industry, Chapter 8, the manufacturing perspective: current approaches to bioprocess intensification;Montgomery;BioProcess. Int.,2017

2. BioPhorum Operations Group Biomanufacturing technology roadmap. Executive summary. 2017, July https://www.biophorum.com/category/resources/technology-roadmapping-resources/introduction/

3. A tandem laboratory scale protein purification process using protein A affinity and anion exchange chromatography operated in a weak partitioning mode;Shamashkin;Biotechnol. Bioeng,2013

4. Integrated continuous production of recombinant therapeutic proteins;Warikoo;Biotechnol. Bioeng,2012

5. Continuous mAb processing;Phillips;Euro Biotech. News,2013

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