Microbial population heterogeneity versus bioreactor heterogeneity: Evaluation of Redox Sensor Green as an exogenous metabolic biosensor

Author:

Baert Jonathan1,Delepierre Anissa1,Telek Samuel1,Fickers Patrick1,Toye Dominique2,Delamotte Anne2,Lara Alvaro R.3,Jaén Karim E.3,Gosset Guillermo4,Jensen Peter R.5,Delvigne Frank1

Affiliation:

1. Gembloux Agro-Bio Tech; Microbial Processes and Interactions (MiPI); University of Liège; Gembloux Belgium

2. Department of Chemical Engineering-Product; Environment and Processes (PEPs); University of Liège; Liège Belgium

3. Departamento de Procesos y Tecnología; Universidad Autónoma Metropolitana-Cuajimalpa; Col. Santa Fe Cuajimalpa México D. F., Mexico

4. Instituto de Biotecnología; Universidad Nacional Autónoma de México; Cuernavaca Morelos México

5. National Food Institute; Technical University of Denmark (DTU); Lyngby Denmark

Funder

Fonds De La Recherche Scientifique - FNRS

Publisher

Wiley

Subject

Bioengineering,Environmental Engineering,Biotechnology

Reference40 articles.

1. Physiological responses to mixing in large scale bioreactors;Enfors;J. Biotechnol.,2001

2. Scale-down simulators for metabolic analysis of large-scale bioprocesses;Neubauer;Curr. Opin. Biotechnol.,2010

3. Modelling of the substrate heterogeneities experienced by a limited microbial population in scale-down and in large-scale bioreactors;Delvigne;Chem. Eng. J.,2006

4. Multi-scale spatio-temporal modeling: Lifelines of microorganisms in bioreactors and tracking molecules in cells;Lapin;Adv. Biochem. Eng. Biotechnol.,2010

5. Microbial heterogeneity affects bioprocess robustness: Dynamic single cell analysis contribute to understanding microbial populations;Delvigne;Biotechnol. J.,2014

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