Mechanism and kinetic study for the intensification of two‐step synthesis of a dolutegravir intermediate in microreactor-Reference-Cited by-同舟云学术

Mechanism and kinetic study for the intensification of two‐step synthesis of a dolutegravir intermediate in microreactor

Published:2022-07-10 Issue:11 Volume:68 Page:
ISSN:0001-1541
Container-title:AIChE Journal
language:en
Short-container-title:AIChE Journal

Author:

Xue Xiao¹^ORCID,Jiang Rongkun²^ORCID,Xie Chengmin¹,Qian Guozhi¹,Shang Minjing¹,Zhu Weiping²,Su Yuanhai¹³^ORCID

Affiliation:

1. Department of Chemical Engineering, School of Chemistry and Chemical Engineering Shanghai Jiao Tong University Shanghai China

2. State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy East China University of Science and Technology Shanghai China

3. Key Laboratory of Thin Film and Microfabrication (Ministry of Education) Shanghai Jiao Tong University Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemical Engineering,Environmental Engineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/aic.17820

Reference37 articles.

1. Structure Based Drug Design: Clinically Relevant HIV-1 Integrase Inhibitors

2. Successful prevention of HIV mother-to-child transmission with dolutegravir-based combination antiretroviral therapy in a vertically infected pregnant woman with multiclass highly drug-resistant HIV-1

3. An Improved Preparation of (R)-3-Aminobutanol, a Key Intermediate for the Synthesis of Dolutegravir Sodium

4. Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

5. A simple and convenient route for the synthesis of (R)‐3‐aminobutanol, an intermediate for the synthesis of dolutegravir;Yatcherla SR;Heterocyc Lett,2015

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