Delayed treatment effects, treatment switching and heterogeneous patient populations: How to design and analyze RCTs in oncology
Author:
Affiliation:
1. Center for Medical Statistics, Informatics, and Intelligent Systems Medical University of Vienna Vienna Austria
2. Merck Healthcare KGaA Darmstadt Germany
Funder
Merck
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/pst.2062
Reference35 articles.
1. Lessons from randomized phase III studies with active cancer immunotherapies – Outcomes from the 2006 Meeting of the Cancer Vaccine Consortium (CVC)
2. AnagnostouV YarchoanM HansenAR WangH VerdeF SharonE CollyarD ChowLQ FordePM.Immuno‐oncology trial endpoints: capturing clinically meaningful activity;2017.
3. Epidermal growth factor receptor (egfr) inhibitors for metastatic colorectal cancer;Chan DLH;Cochrane Database Syst Rev,2017
4. Predicting analysis times in randomized clinical trials with cancer immunotherapy
5. Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
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