Cluster <scp>Gauss‐Newton</scp> method analyses of <scp>PBPK</scp> model parameter combinations of <scp>coproporphyrin‐I</scp> based on <scp>OATP1B</scp> ‐mediated rifampicin interaction studies-Reference-Cited by-同舟云学术

Cluster Gauss‐Newton method analyses of PBPK model parameter combinations of coproporphyrin‐I based on OATP1B ‐mediated rifampicin interaction studies

Published:2022-08-09 Issue:10 Volume:11 Page:1341-1357
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacom & Syst Pharma

Author:

Yoshikado Takashi¹,Aoki Yasunori²,Mochizuki Tatsuki³,Rodrigues A. David⁴,Chiba Koji¹^ORCID,Kusuhara Hiroyuki³,Sugiyama Yuichi²

Affiliation:

1. Laboratory of Clinical Pharmacology Yokohama University of Pharmacy Yokohama Kanagawa Japan

2. Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy Josai International University Tokyo Japan

3. Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences the University of Tokyo Tokyo Japan

4. Transporter Sciences Group, ADME Sciences, Medicine Design, Pfizer Groton Connecticut USA

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12849

Reference30 articles.

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2. Transporter-Mediated Drug–Drug Interactions Involving OATP Substrates: Predictions Based on In Vitro Inhibition Studies

3. Understanding the Critical Disposition Pathways of Statins to Assess Drug–Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1

4. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach

5. Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium

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