Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium

Author:

Chu Xiaoyan1,Liao Mingxiang2,Shen Hong3,Yoshida Kenta4ORCID,Zur Arik A.5,Arya Vikram6ORCID,Galetin Aleksandra7,Giacomini Kathleen M.8ORCID,Hanna Imad9,Kusuhara Hiroyuki10,Lai Yurong11ORCID,Rodrigues David12,Sugiyama Yuichi13ORCID,Zamek-Gliszczynski Maciej J.14,Zhang Lei15,

Affiliation:

1. Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism; Merck & Co., Inc; Kenilworth New Jersey USA

2. Department of Clinical Pharmacology; Clovis Oncology, Inc.; Boulder Colorado USA

3. Department of Metabolism and Pharmacokinetics; Bristol-Myers Squibb; Princeton New Jersey USA

4. Clinical Pharmacology; Genentech Research and Early Development; South San Francisco California USA

5. BiolineRX; Modi'in Israel

6. Division of Clinical Pharmacology IV; Office of Clinical Pharmacology; Office of Translational Sciences; Center for Drug Evaluation and Research; Food and Drug Administration; Silver Spring Maryland USA

7. Centre for Applied Pharmacokinetic Research; School of Health Sciences; University of Manchester; Manchester UK

8. Department of Bioengineering and Therapeutic Sciences; Schools of Pharmacy and Medicine; University of California; San Francisco California USA

9. Pharmacokinetic Sciences; Novartis Institutes for Biomedical Research; East Hanover New Jersey USA

10. Graduate School of Pharmaceutical Sciences; The University of Tokyo; Tokyo Japan

11. Drug Metabolism; Gilead Science, Inc.; Foster City California USA

12. Pharmacokinetics, Dynamics, & Metabolism; Medicine Design; Pfizer Inc.; Groton Connecticut USA

13. Sugiyama Laboratory; RIKEN Baton Zone Program, Cluster for Science; RIKEN; Yokohama Japan

14. Quantitative Drug Disposition; GlaxoSmithKline PLC; King of Prussia Pennsylvania USA

15. Office of Research and Standards; Office of Generic Drugs; Center for Drug Evaluation and Research; Food and Drug Administration; Silver Spring Maryland USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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