Synthesis of the N ‐methyl Derivatives of 2‐Aminothiazol‐4(5 H )‐one and Their Interactions with 11 β HSD1‐Molecular Modeling and in Vitro Studies-Reference-Cited by-同舟云学术

Synthesis of the N ‐methyl Derivatives of 2‐Aminothiazol‐4(5 H )‐one and Their Interactions with 11 β HSD1‐Molecular Modeling and in Vitro Studies

Published:2019-06-06 Issue: Volume: Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:C&B

Author:

Studzińska Renata¹^ORCID,Kołodziejska Renata²,Płaziński Wojciech³,Kupczyk Daria²,Kosmalski Tomasz¹,Jasieniecka Katarzyna¹,Modzelewska‐Banachiewicz Bożena¹

Affiliation:

1. Department of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in BydgoszczNicolaus Copernicus University in Toruń, Jurasza 2 85-089 Bydgoszcz Poland

2. Department of Medical Biology and Biochemistry, Faculty of Medicine, Collegium Medicum in BydgoszczNicolaus Copernicus University in Toruń, Karłowicza 24 85-092 Bydgoszcz Poland

3. J. Haber Institute of Catalysis and Surface ChemistryPolish Academy of Sciences Niezapominajek Str. 8 30-239 Cracow Poland

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.201900065

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1. Lipophilic Studies and In Silico ADME Profiling of Biologically Active 2-Aminothiazol-4(5H)-one Derivatives;International Journal of Molecular Sciences;2023-07-31

2. Synthesis of Novel 2-(Cyclopentylamino)thiazol-4(5H)-one Derivatives with Potential Anticancer, Antioxidant, and 11β-HSD Inhibitory Activities;International Journal of Molecular Sciences;2023-04-14

3. 11β-Hydroxysteroid Dehydrogenase Type 1 as a Potential Treatment Target in Cardiovascular Diseases;Journal of Clinical Medicine;2022-10-20

4. 11β-HSD as a New Target in Pharmacotherapy of Metabolic Diseases;International Journal of Molecular Sciences;2022-08-11

5. Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1—Synthesis, Molecular Docking and In Vitro Studies;International Journal of Molecular Sciences;2021-08-10