Hybrid Pharmacophoric Approach in the Design and Synthesis of Coumarin Linked Pyrazolinyl as Urease Inhibitors, Kinetic Mechanism and Molecular Docking

Author:

Saeed Aamer1,Mahesar Parvez Ali1,Channar Pervaiz Ali1,Larik Fayaz Ali1,Abbas Qamar2,Hassan Mubashir2,Raza Hussain2,Seo Sung-Yum2

Affiliation:

1. Department of Chemistry; Quaid-I-Azam University; Islamabad 45320 Pakistan

2. Department of Biological Sciences; College of Natural Sciences; Kongju National University; 56 Gongjudehak-Ro Gongju Chungnam 314-701 Korea

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference43 articles.

1. Urease Inhibitors: A Review;Upadhyay;Indian J. Biotechnol.,2012

2. Carbonic Anhydrase Inhibition by 1-Aroyl-3-(4-aminosulfonylphenyl)thioureas;Saeed;J. Enzyme Inhib. Med. Chem.,2014

3. Urease Inhibitors of Agricultural Interest Inspired by Structures of Plant Phenolic Aldehydes;Horta;J. Braz. Chem. Soc.,2016

4. Biscoumarin: New Class of Urease Inhibitors; Economical Synthesis and Activity;Khan;Bioorg. Med. Chem.,2004

5. Urease Inhibitors from Hypericum oblongifolium Wall.;Arfan;J. Enzyme Inhib. Med. Chem.,2010

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