An NIR‐based PAT approach for real‐time control of loading in Protein A chromatography in continuous manufacturing of monoclonal antibodies

Author:

Thakur Garima1,Hebbi Vishwanath1,Rathore Anurag S.1ORCID

Affiliation:

1. Department of Chemical EngineeringIndian Institute of Technology New Delhi India

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference23 articles.

1. Design and control of integrated chromatography column sequences

2. Definition and dynamic control of a continuous chromatography process independent of cell culture titer and impurities

3. CMC Biotech Working Group. (2009).A‐Mab: a case study in bioprocess development. InCASSS Emeryville(http://casss.org/associations/9165/files/A‐Mab_Case_Study_Version_2‐1.pdf

4. Real-time control of antibody loading during protein A affinity chromatography using an on-line assay

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