Definition and dynamic control of a continuous chromatography process independent of cell culture titer and impurities

Author:

Chmielowski Rebecca A.,Mathiasson Linda,Blom Hans,Go Daniel,Ehring Hanno,Khan Heera,Li Hong,Cutler Collette,Lacki Karol,Tugcu Nihal,Roush David

Funder

Merck & Co

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference27 articles.

1. Practical use of continuous processing in developing and scaling up laboratory processes;Anderson;Org. Process Res. Dev.,2001

2. Continuous Processing in Pharmaceutical Manufacturing;Subramanian,2015

3. Regulatory and Quality Considerations for Continuous Manufacturing, Presentation at the International Symposium on Continuous Manufacturing of Pharmaceuticals: Implementation, Technology, & Regulatory;Allison,2014

4. FDA perspective on continuous manufacturing;Chatterjee,2012

5. Adapting viral safety assurance strategies to continuous processing of biological products;Johnson;Biotechnol. Bioeng.,2017

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