Substrate Flexibility of the Flavin‐Dependent Dihydropyrrole Oxidases PigB and HapB Involved in Antibiotic Prodigiosin Biosynthesis-Reference-Cited by-同舟云学术

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Substrate Flexibility of the Flavin‐Dependent Dihydropyrrole Oxidases PigB and HapB Involved in Antibiotic Prodigiosin Biosynthesis

Published:2019-10-21 Issue:4 Volume:21 Page:523-530
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Couturier Maxime¹,Bhalara Hiral D.¹,Chawrai Suresh R.¹,Monson Rita²,Williamson Neil R.²,Salmond George P. C.²,Leeper Finian J.¹^ORCID

Affiliation:

1. Department of ChemistryUniversity of Cambridge Lensfield Road Cambridge CB2 1EW UK

2. Department of BiochemistryUniversity of Cambridge Tennis Court Road Cambridge CB2 1QW UK

Funder

Frances and Augustus Newman Foundation

Cambridge Commonwealth Trust

Emmanuel College, University of Cambridge

Biotechnology and Biological Sciences Research Council

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201900424

Reference43 articles.

1. Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells

2. Synthesis and Immunosuppressive Activity of Novel Prodigiosin Derivatives

3. Antimalarial Activity of Prodigiosin

4. Antimicrobial activity of prodigiosin isolated from Serratia marcescens UFPEDA 398

5. Prodigiosin and its potential applications

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1. Production of tailored hydroxylated prodiginine showing combinatorial activity with rhamnolipids against plant-parasitic nematodes;Frontiers in Microbiology;2023-05-02

2. The convergence of bacterial natural products from evolutionarily distinct pathways;Current Opinion in Biotechnology;2021-06

3. Chitin Degradation Machinery and Secondary Metabolite Profiles in the Marine Bacterium Pseudoalteromonas rubra S4059;Marine Drugs;2021-02-12

4. Revision in the first steps of the biosynthesis of the red antibiotic prodigiosin: use of a synthetic thioester to validate a new intermediate;RSC Chemical Biology;2021

5. Understanding substrate binding and the role of gatekeeping residues in PigC access tunnels;Chemical Communications;2021

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