AGT Activity Towards Intrastrand Crosslinked DNA is Modulated by the Alkylene Linker-Reference-Cited by-同舟云学术

AGT Activity Towards Intrastrand Crosslinked DNA is Modulated by the Alkylene Linker

Published:2017-11-07 Issue:23 Volume:18 Page:2351-2357
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

O'Flaherty Derek K.¹²^ORCID,Wilds Christopher J.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry; Concordia University Montreal; 7141 Sherbrooke Street W. Montreal Quebec H4B 1R6 Canada

2. Present address: Howard Hughes Medical Institute; Department of Molecular Biology and; Center for Computational and Integrative Biology; Massachusetts General Hospital; Boston MA 02114 USA

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference48 articles.

1. Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools

2. Pyridyloxobutyl Adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine Is Present in 4-(Acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-Treated DNA and Is a Substrate for O6-Alkylguanine-DNA Alkyltransferase

3. Repair of O6-G-Alkyl-O6-G Interstrand Cross-Links by Human O6-Alkylguanine-DNA Alkyltransferase

4. Synthesis and characterization of an O6-2′-deoxyguanosine-alkyl-O6-2′-deoxyguanosine interstrand cross-link in a 5′-GNC motif and repair by human O6-alkylguanine-DNA alkyltransferase

5. The effectiveness of the O6-alkylguanine-DNA alkyltransferase encoded by the ogtST gene from S. typhimurium in protection against alkylating drugs, resistance to O6-benzylguanine and sensitisation to dibromoalkane genotoxicity

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Covalent capture of OGT's active site using engineered human-E. coli chimera and intrastrand DNA cross-links;Organic & Biomolecular Chemistry;2018