Covalent capture of OGT's active site using engineered human-E. coli chimera and intrastrand DNA cross-links
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. Concordia University
3. Montréal
4. Canada
5. Department of Molecular Biology and Center for Computational and Integrative Biology
Abstract
Intrastrand crosslinked DNA has been shown to react with an AGT variant to produce well-defined protein–DNA conjugates.
Funder
Natural Sciences and Engineering Research Council of Canada
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02453G
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