The Biosynthetic Gene Cluster of Pyrazomycin—A C‐Nucleoside Antibiotic with a Rare Pyrazole Moiety-Reference-Cited by-同舟云学术

The Biosynthetic Gene Cluster of Pyrazomycin—A C‐Nucleoside Antibiotic with a Rare Pyrazole Moiety

Published:2019-11-20 Issue:5 Volume:21 Page:644-649
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Zhao Guiyun¹,Yao Shunyu¹,Rothchild Kristina W.²,Liu Tengfei³,Liu Yu⁴,Lian Jiazhang³,He Hai‐Yan²,Ryan Katherine S.²,Du Yi‐Ling¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Biotechnology and The First Affiliated HospitalZhejiang University School of Medicine 866 Yuhangtang Road Hangzhou 310058 P. R. China

2. Department of ChemistryThe University of British Columbia 2036 Main Mall Vancouver BC V6T 1Z1 Canada

3. Institute of Biological Engineering, College of Chemical and Biological EngineeringZhejiang University 38 Zheda Road Hangzhou 310027 P. R. China

4. College of Life SciencesZhejiang University 866 Yuhangtang Road Hangzhou 310058 P. R. China

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Natural Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201900449

Reference27 articles.

1. Natural Products Containing a Nitrogen–Nitrogen Bond

2. A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate

3. An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

4. Two-Enzyme Pathway Links l-Arginine to Nitric Oxide in N-Nitroso Biosynthesis

5. A nitrous acid biosynthetic pathway for diazo group formation in bacteria

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