Nonenzymatic Oligomerization of 3′,5′-Cyclic CMP Induced by Proton and UV Irradiation Hints at a Nonfastidious Origin of RNA

Author:

Costanzo Giovanna1,Giorgi Alessandra2,Scipioni Anita3,Timperio Anna Maria4,Mancone Carmine56,Tripodi Marco56,Kapralov Michail7,Krasavin Eugene7,Kruse Holger8,Šponer Jiří89,Šponer Judit E.8ORCID,Ranc Václav9,Otyepka Michal9,Pino Samanta10,Di Mauro Ernesto10

Affiliation:

1. Istituto di Biologia e Patologia Molecolari; CNR; Piazzale Aldo Moro 5 00185 Rome Italy

2. Dipartimento di Scienze Biochimiche; “Sapienza” Università di Roma; Piazzale Aldo Moro 5 00185 Rome Italy

3. Dipartimento di Chimica; “Sapienza” Università di Roma; Piazzale Aldo Moro 5 00185 Rome Italy

4. Department of Ecology and Biology; “La Tuscia” University; Viale dell'Università snc 01100 Viterbo Italy

5. Department of Cellular Biotechnologies and Hematology; Sapienza University of Rome; Via Regina Elena 324 00161 Roma Italy

6. National Institute for Infectious Diseases “L. Spallanzani”; IRCCS; Via Portuense 292 00149 Rome Italy

7. Joint Institute for Nuclear Research; Laboratory of Radiation Biology; 141980 Dubna Russia

8. Institute of Biophysics; Academy of Sciences of the Czech Republic; Královopolská 135 61265 Brno Czech Republic

9. Regional Centre of Advanced Technologies and Materials; Department of Physical Chemistry; Faculty of Science; Palacky University; 17. Listopadu 771 46 Olomouc Czech Republic

10. Department of Biology and Biotechnology; Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti; Sapienza University of Rome; Piazzale Aldo Moro 5 00185 Rome Italy

Funder

Agenzia Spaziale Italiana

Grantová Agentura České Republiky

Joint Institute for Nuclear Research

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

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