Synthesis and in Vitro Characterization of Trehalose-Based Inhibitors of Mycobacterial Trehalose 6-Phosphate Phosphatases
Author:
Affiliation:
1. Department of Chemistry and Biochemistry; School of Green Chemistry and Engineering; The University of Toledo; 2801 West Bancroft Street Toledo Ohio 43606 USA
2. EMBL Hamburg; c/o DESY, Building 25A Notkestrasse 85 22603 Hamburg Germany
Funder
National Institute of Allergy and Infectious Diseases
Publisher
Wiley
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201800551/fullpdf
Reference45 articles.
1. A Tale of Two Sugars: Trehalose 6-Phosphate and Sucrose
2. Physiological roles of trehalose in bacteria and yeasts: a comparative analysis
3. Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases
4. The regulation of trehalose metabolism in insects
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