Preoperative intraparietal (intra-incisional) cefoxitin in abdominal surgery

Author:

Taylor T V1,Walker W S1,Mason R C1,Richmond J1,Lee D1

Affiliation:

1. Department of Clinical Surgery, Royal Infirmary, Edinburgh, Scotland

Abstract

Abstract The effect of preoperative intraparietal (intra-incisional) injection of cefoxitin along the site of the intended incision on the incidence of wound infection has been investigated by a randomized prospective study of 181 consecutive patients undergoing abdominal surgery. A significant reduction in wound infection was evident in the cefoxitin-treated group (4·4 per cent) when compared with controls (16·7 per cent) (χ2 = 6; P = 0·02). Administration of antibiotic by this route did not delay wound healing or produce any undesirable sequelae.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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