1. Faculty of Pharmaceutical Sciences Tokyo University of Science 2641 Yamazaki Noda Chiba 278-8510 Japan
2. Division of Fusion of Regenerative Medicine with DDS Research Institute for Science and Technology (RIST) Tokyo University of Science 2641 Yamazaki Noda Chiba 278-8510 Japan
3. Current address: Faculty of Pharmaceutical Sciences Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-tobetsu Hokkaido 0610-293 Japan