Pharmacokinetic characterization of BMS-936561, an anti-CD70 antibody-drug conjugate, in preclinical animal species and prediction of its pharmacokinetics in humans

Author:

Wang Haiqing1,Rangan Vangipuram S.2,Sung Mei-Chen2,Passmore David2,Kempe Thomas2,Wang Xiaoli3,Thevanayagam Lourdes2,Pan Chin2,Rao Chetana2,Srinivasan Mohan2,Zhang Qian2,Gangwar Sanjeev2,Deshpande Shrikant2,Cardarelli Pina2,Marathe Punit1,Yang Zheng1

Affiliation:

1. Metabolism and Pharmacokinetics; Bristol-Myers Squibb; Princeton NJ United States

2. Biologics Discovery California; Bristol-Myers Squibb; Redwood City CA United States

3. Clinical Pharmacology; Bristol-Myers Squibb; Princeton NJ United States

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference37 articles.

1. Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor;Goodwin;Cell,1993

2. The cloning of CD70 and its identification as the ligand for CD27;Bowman;J Immunol,1994

3. CD70 represents the human ligand for CD27;Hintzen;Int Immunol,1994

4. Characterization of the human CD27 ligand, a novel member of the TNF gene family;Hintzen;J Immunol,1994

5. CD70 represents the human ligand for CD27;Hintzen;Int Immunol,1994

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