Labda-8(17),12,14-trien-19-oic Acid Contained in Fruits ofCupressus sempervirensSuppresses Benign Prostatic Hyperplasia in Rat andIn VitroHuman Models Through Inhibition of Androgen and STAT-3 Signaling

Author:

Verma Vikas1,Sharma Vikas1,Singh Vishal1,Kumar Rajeev1,Khan Mohammad F.2,Singh Anil K.3,Sharma Rolee4,Arya Kamal R.5,Maikhuri J.P.1,Dalela Diwakar6,Maurya Rakesh2,Gupta Gopal1

Affiliation:

1. Division of Endocrinology; CSIR-Central Drug Research Institute; Lucknow 226 001 India

2. Division of Medicinal and Process Chemistry; CSIR-Central Drug Research Institute; Lucknow 226 001 India

3. Department of Physics and Computer Science; Ewing Christian College; Allahabad 211003 India

4. Department of Biotechnology; Integral University; Lucknow 226026 India

5. Division of Botany; CSIR-Central Drug Research Institute; Lucknow 226 001 India

6. Department of Urology; CSM Medical University; Lucknow 226 003 India

Publisher

Wiley

Subject

Pharmacology

Reference26 articles.

1. AUA guideline on management of benign prostatic hyperplasia 2003. Chapter 1: Diagnosis and treatment recommendations;AUA;J Urol,2003

2. Insulin-like growth factor-I (IGF-I) and its binding protein IGFBP-4 in human prostatic hyperplastic tissue: gene expression and its cellular localization;Barni;J Clin Endocrinol Metab,1994

3. Benign prostatic hyperplasia and normal prostate aging: differences in types I and II 5 alpha-reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels, but not in insulin-like growth factor mRNA levels;Bonnet;J Clin Endocrinol Metab,1993

4. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients;Carraro;Prostate,1996

5. Videoimaging of prostatic stromal-cell contraction: an in vitro model for studying drug effects;Corvin;Prostate,1998

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